Calprofen Ibuprofen Suspension Sachets, Sugar & Colour Free, Pain & Fever Relief for 3+ Months, Strawberry Flavour, 5 ml, 12-Count

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Excipients: Maltitol, Sodium methylhydroxybenzoate, sodium propylhydroxybenzoate, Propylene glycol and Sodium. Severe hepatic failure, renal failure and heart failure (NYHA Class IV) (see section 4.4, Special warnings and precautions for use). It's best to give ibuprofen to children with food or milk so that they do not get indigestion. Liquid (oral suspension) The administration of an NSAID may cause a dose dependent reduction in prostaglandin formation and precipitate renal failure. The habitual concomitant intake of various similar painkillers further increases this risk. Patients at greatest risk of this reaction are those with impaired renal function, cardiac impairment, liver dysfunction, those taking diuretics and the elderly. For these patients, use the lowest effective dose, for the shortest possible duration and monitor renal function especially in long-term treated patients (see also section 4.3).

In the limited studies so far available, NSAIDs can appear in the breast milk in very low concentrations. NSAIDs should, if possible, be avoided when breastfeeding. Always follow your doctor or pharmacist's advice, and the instructions that come with your medicine. Dosage and strength for tablets, capsules, granules and liquidQuinolone antibiotics: Animal data indicate that NSAIDs can increase the risk of convulsions associated with quinolone antibiotics. Patients taking NSAIDs and quinolones may have an increased risk of developing convulsions. The administration of an NSAID may cause a dose dependent reduction in prostaglandin formation and precipitate renal failure. The habitual concomitant intake of various similar painkillers further increases this risk. Patients at greatest risk of this reaction are those with impaired renal function, cardiac impairment, liver dysfunction, those taking diuretics and the elderly. For these patients, use the lowest effective dose, for the shortest possible duration and monitor renal function especially in long-term treated patients (see also section 4.3). Aminoglycosides : NSAIDs may decrease the excretion of aminoglycosides. Herbal extracts : Ginkgo biloba may potentiate the risk of bleeding with NSAIDs. CYP2C9 Inhibitors : Concomitant administration of ibuprofen with CYP2C9 Anticoagulants: NSAIDs may enhance the effects of anticoagulants, such as warfarin (see section 4.4). Pharmacotherapeutic group: Anti-inflammatory and antirheumatic products, nonsteroidal; propionic acid derivatives.

Nephrotoxity in various forms e.g.Tubulointerstitial nephritis, nephrotic syndrome and renal failure Prescription Only: Ibuprofen 100 mg / 5 ml Oral Suspension is indicated for its analgesic and anti-inflammatory effects in the treatment of dysmenorrhoea, neuralgia, post–operative pain, rheumatoid arthritis (including juvenile rheumatoid arthritis or Still's disease), ankylosing spondylitis, osteoarthritis and other non-rheumatoid (seronegative) arthropathies.Clinical studies suggest that use of Ibuprofen, particularly at a high dose (2400 mg/day) may be associated with a small increased risk of arterial thrombotic events (for example myocardial infarction or stroke). Overall, epidemiological studies do not suggest that low dose ibuprofen (e.g. ≤1200 mg/day) is associated with an increased risk of arterial thrombotic events. Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms (see section 4.2, and GI and cardiovascular risks below). As with other NSAIDs, ibuprofen may mask the signs of infection. If you're taking ibuprofen for a short-lived pain like toothache or period pain, you may only need to take it for a day or two. Experimental data suggest that ibuprofen may competitively inhibit the effect of low dose aspirin on platelet aggregation when they are dosed concomitantly. Although there are uncertainties regarding extrapolation of these data to the clinical situation, the possibility that regular, long-term use of ibuprofen may reduce the cardioprotective effect of low-dose acetylsalicylic acid cannot be excluded. No clinically relevant effect is considered to be likely for occasional use (see section 5.1).